Alzheimers Dementia Treatment
The goal of therapy in Alzheimer dementia is to increase acetylcholine levels with acetylcholinesterase inhibitors, such as donepezil, rivastigmine, galantamine, and tacrine. Donepezil has a better side effect profile as when compared with other available pharmacotherapies. Tacrine is not frequently used anymore because of its hepatotoxicity.
Memantine is an NMDA receptor antagonist that is neuroprotective in patients who have moderate to severe Alzheimer disease.
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